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Chemical Structure : ALESIA
Catalog No.: PC-72841Not For Human Use, Lab Use Only.
ALESIA is a sphingosine-1-phosphate receptor 3 (S1PR3)-G12-biased agonist and selectively induces G12 signal.
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ALESIA is a specific sphingosine-1-phosphate receptor 3 (S1PR3)-G12-biased agonist and selectively induces G12 signal.
ALESIA promotes nitric oxide production and oxidative stress.
ALESIA selectively induces apoptosis in cancer cells because of low glucose levels.
Intraperitoneal administration of ALESIA improved the survival of mice with peritoneally disseminated rhabdomyosarcoma.
ALESIA (Anticancer Ligand Enhancing Starvation-induced Apoptosis) is a new anticancer compound for glucose starvation therapy.
| M.Wt | 456.5 | |
| Formula | C22H24F4N2O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Masayasu Toyomoto, et al. Cell Chem Biol. 2021 Aug 19;28(8):1132-1144.e9.
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