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Chemical Structure : ALK2 R206H inhibitor 23
Catalog No.: PC-72134Not For Human Use, Lab Use Only.
ALK2 R206H inhibitor 23 is a potent and selective inhibitor of Activin Receptor-Like Kinase-2 (ALK2/ACVR1) with IC50 of 8 nM for mutant ALK2 R206H.
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ALK2 R206H inhibitor 23 is a potent and selective inhibitor of Activin Receptor-Like Kinase-2 (ALK2/ACVR1) with IC50 of 8 nM for mutant ALK2 R206H.
ALK2 R206H inhibitor 23 displays >15-fold selectivity over ALK1/ALK3, and >100-fold over ALK5/ALK6.
| M.Wt | 555.12 | |
| Formula | C29H39ClN6O3 | |
| Appearance | Solid | |
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1. Bioorg Med Chem Lett. 2022 Mar 8;128667.
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