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Chemical Structure : ALLM
CAS No.: 136632-32-1
Catalog No.: PC-70124Not For Human Use, Lab Use Only.
ALLM (Ac-Leu-Leu-Met-CHO) is a potent, cell-permeable calpain inhibitor with Ki of 0.6 and 100 nM for calpain L and calpain B, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 25 mg | $498 | In stock | |
| 100 mg | Get quote | ||
| 200 mg | Get quote | ||
| 1 g | Get quote |
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ALLM (Ac-Leu-Leu-Met-CHO) is a potent, cell-permeable calpain inhibitor with Ki of 0.6 and 100 nM for calpain L and calpain B, respectively.
ALLM inhibits the activities of Ca(2+)-dependent neutral proteases as well as lysosomal proteases, including cathepsin L, cathepsin B, and cathepsin D.
ALLM induces apoptosis in rat pituitary tumor cells by specific caspase activation.
| M.Wt | 401.57 | |
| Formula | C19H35N3O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-Acetyl-L-leucyl-L-leucyl-L-methional |
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1. Neumann D, et al. Biochem J. 1996 Jan 15;313 ( Pt 2):391-9.
2. Inoue S, et al. J Biol Chem. 1991 Jul 15;266(20):13311-7.
3. Yu R, et al. J Endocrinol. 2002 Sep;174(3):379-86.
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