AM4085 | FmlH Lectin inhibitor | Probechem Biochemicals

Chemical Structure : AM4085

AM4085 (AM 4085)

Catalog No.: PC-21823Not For Human Use, Lab Use Only.

AM4085 is a potent, orally bioavailable lectin domain of FmLH antagonist with IC50 of 0.19 uM.

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Biological Activity

AM4085 is a potent, orally bioavailable lectin domain of FmLH antagonist with IC50 of 0.19 uM.
AM4085 a promising lead candidate worthy of further potency optimization and biological evaluation in advanced preclinical studies in the treatment of chronic urinary tract infections (UTIs) of the bladder and kidney.

Physicochemical Properties

M.Wt	459.39
Formula	C21H21F4NO6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((2S,3R,4R,5R,6R)-2-((4'-fluoro-6-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide

References

1. Maddirala AR, et al. J Med Chem. 2024 Feb 3. doi: 10.1021/acs.jmedchem.3c02128.

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AM4085 (AM 4085)

Biological Activity

Physicochemical Properties

References

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