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Chemical Structure : AM6580
Catalog No.: PC-73016Not For Human Use, Lab Use Only.
AM6580 is a potent, covalent monoacylglycerol lipase (MAGL) inhibitor with IC50 of 3 nM (hMAGL).
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AM6580 is a potent, covalent monoacylglycerol lipase (MAGL) inhibitor with IC50 of 3 nM (hMAGL).
AM6580 covalently binds to and inactivates MAGL by carbamylation of the enzyme's catalytic Ser122 nucleophile.
| M.Wt | 396.454 | |
| Formula | C23H20N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Benchama O, et al. Sci Rep. 2022 Mar 29;12(1):5328.
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