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APC24-7

Chemical Structure : APC24-7

CAS No.: 3128355-04-1

APC24-7 (APC 24-7)

Catalog No.: PC-28699Not For Human Use, Lab Use Only.

APC24-7 is a covalent combination of boronic acid and chelator moieties, restores β-lactam efficiency against metallo-β-lactamase-producers, sensitizesclinical isolates of SBL- and MBL-producing Klebsiella pneumoniae and Escherichia coli to meropenem.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

APC24-7 is a covalent combination of boronic acid and chelator moieties, restores β-lactam efficiency against metallo-β-lactamase-producers, sensitizesclinical isolates of SBL- and MBL-producing Klebsiella pneumoniae and Escherichia coli to meropenem.

Physicochemical Properties

M.Wt 565.44
Formula C31H32BN5O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-3-(4-(((2-(bis(pyridin-2-ylmethyl)amino)ethyl)amino)methyl)benzamido)-2-hydroxy-3,4-dihydro-2H-benzo[e][1,2]oxaborinine-8-carboxylic acid

References

1. Hovd RR, et al. mSphere. 2025 Dec 23;10(12):e0041825.

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