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Chemical Structure : APS6-45
CAS No.: 2188236-41-9
Catalog No.: PC-38595Not For Human Use, Lab Use Only.
APS6-45 is an orally active tumor-calibrated inhibitor (TCI) that inhibits RAS/MAPK signaling and exhibits antitumor activity.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $228 | In stock | |
| 10 mg | $378 | In stock | |
| 50 mg | $858 | In stock | |
| 100 mg | $1480 | In stock | |
| 1 g | Get quote |
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SB-224289 is a potent 5-HT1B inverse agonist (pKi = 8.16) that displays >75-fold selectivity for human 5-HT1B over all other 5-HT receptors.
| M.Wt | 548.39 | |
| Formula | C23H16F8N4O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-[4-[[[[2-Fluoro-5-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
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1. Sonoshita M, et, al. Nat Chem Biol. 2018 Mar;14(3):291-298.
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