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APX2020

Chemical Structure : APX2020

CAS No.: 936339-59-2

APX2020

Catalog No.: PC-23301Not For Human Use, Lab Use Only.

APX2020 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.016-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

APX2020 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.016-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans.

Physicochemical Properties

M.Wt 357.41
Formula C22H19N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(3-(4-(benzyloxy)benzyl)isoxazol-5-yl)pyridin-2-amine

References

1. Karen Joy Shaw, et al. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00523-18.

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