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Chemical Structure : AR-C102222
Catalog No.: PC-62230Not For Human Use, Lab Use Only.
AR-C102222 is a potent, selective iNOS inhibitor with IC50 of 35 nM, dislapys 3,000-fold and 20-fold selectivity over eNOS and nNOS respectively.
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AR-C102222 is a potent, selective iNOS inhibitor with IC50 of 35 nM, dislapys 3,000-fold and 20-fold selectivity over eNOS and nNOS respectively.
AR-C102222 reduces inflammation produced by the application of arachidonic acid to the ear, attenuates FCA-induced mechanical hyperalgesia, and attenuates acetic acid-induced writhing in mice.
| M.Wt | 382.375 | |
| Formula | C19H16F2N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Garcin ED, et al. Nat Chem Biol. 2008 Nov;4(11):700-7.
2. Tinker AC, et al. J Med Chem. 2003 Mar 13;46(6):913-6.
3. LaBuda CJ, et al. Eur J Pain. 2006 Aug;10(6):505-12.
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