You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-Proton Pump-AR-HO47108
AR-HO47108

Chemical Structure : AR-HO47108

CAS No.: 248281-68-7

AR-HO47108 (AR HO47108)

Catalog No.: PC-62959Not For Human Use, Lab Use Only.

AR-HO47108 is a potent, selective acid pump antagonist (potassium-competitive acid blocker or P-CAB) that reversiblely inhibits gastric H+/K+-ATPase with pIC50 of 7.0.

Packing Price Stock Quantity
100 mg Get quote
250 mg Get quote
500 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AR-HO47108 is a potent, selective acid pump antagonist (potassium-competitive acid blocker or P-CAB) that reversiblely inhibits gastric H+/K+-ATPase with pIC50 of 7.0; shows efficacy in animal models of gastric acid secretion.

Physicochemical Properties

M.Wt 336.439
Formula C20H24N4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8-((2-ethyl-6-methylbenzyl)amino)-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxamide

References

1. Abelö A, et al. Eur J Pharm Sci. 2006 Oct 1;29(2):91-101. Epub 2006 Jun 9.

2. Bailey N, et al. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3602-6.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: