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AR244555

Chemical Structure : AR244555

CAS No.: 858350-62-6

AR244555

Catalog No.: PC-24411Not For Human Use, Lab Use Only.

AR244555 is a specific, non-peptide inverse agonist of G protein-coupled receptor Mas with IC50 of 186 and 348 nM for human and rat Mas receptor respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AR244555 is a specific, non-peptide inverse agonist of G protein-coupled receptor Mas with IC50 of 186 and 348 nM for human and rat Mas receptor respectively.

Physicochemical Properties

M.Wt 416.90
Formula C23H23ClF2N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Methanone, [1′-(3-buten-1-yl)-5-chloro-1,2-dihydrospiro[3H-indole-3,4′-piperidin]-1-yl](2,6-difluorophenyl)-

References

1. Arunachal Chatterjee, et al. PLoS One. 2017 Dec 29;12(12):e0190217.

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