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Chemical Structure : ARP101
Catalog No.: PC-35730Not For Human Use, Lab Use Only.
ARP101 (ARP-101) is a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells.
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ARP101 (ARP-101) is a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells.
ARP101 (ARP-101) was highly effective in inducing the formation of autophagosome and conversion of LC3I into LC3II.
ARP101-induced autophagy was completely blocked in mouse embryo fibroblasts that lacked autophagy related gene 5 (ATG5(-/-) MEF).
ARP101 inhibits α-MSH-stimulated melanogenesis by regulation of autophagy in melanocytes.
| M.Wt | 406.497 | |
| Formula | C20H26N2O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jo YK, et al. Biochem Biophys Res Commun. 2011 Jan 28;404(4):1039-43.
2. Kim ES, et al. FEBS Lett. 2013 Dec 11;587(24):3955-60.
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