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ATC12

Chemical Structure : ATC12

CAS No.:

ATC12

Catalog No.: PC-26460Not For Human Use, Lab Use Only.

ATC12 is a specific small molecule inhibitor of Aurora-A/TPX2 interactionwith IC50 of 25.6 uM, binds Aurora-A and to compete with TPX2.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ATC12 is a specific small molecule inhibitor of Aurora-A/TPX2 interactionwith IC50 of 25.6 uM, binds Aurora-A and to compete with TPX2.

Physicochemical Properties

M.Wt 441.57
Formula C29H31NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

methyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)benzo[f]quinoline-1-carboxylate

References

1. Boi D, et al. Cell Death Dis. 2026 Mar 24. doi: 10.1038/s41419-026-08579-3.

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