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Chemical Structure : AZ12204657
Catalog No.: PC-35910Not For Human Use, Lab Use Only.
AZ12204657 (AZ-12204657) small-molecule GPR44 antagonist, displaces the binding of [3H]PGD2 from membranes of HEK293 cells transfected with human recombinant GPR44 with IC50 of 2.5 nM.
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AZ12204657 (AZ-12204657) small-molecule GPR44 antagonist, displaces the binding of [3H]PGD2 from membranes of HEK293 cells transfected with human recombinant GPR44 with IC50 of 2.5 nM; [11C]AZ12204657 is a potential PET radioligand for the beta cell-restricted protein GPR44.
| M.Wt | 405.242 | |
| Formula | C16H14Cl2O6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Eriksson O, et al. Diabetes. 2018 Feb;67(2):182-192.
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