Chemical Structure : AZ12799734
CAS No.:
1117684-36-2
AZ12799734
(AZ-12799734;AZ 12799734)
Catalog No. : PC-35812Not For Human Use, Lab Use Only.
AZ12799734 (AZ-12799734) is a pan BMP/TGFβ inhibitor that potently inhibits ligand activated SMAD3/4 transcription with IC50 of 47 nM.
Packing Price Stock Quantity 5 mg $128 In stock 0 1 2 3 4 5 10 mg $198 In stock 0 1 2 3 4 5 25 mg $348 In stock 0 1 2 3 4 5 50 mg $548 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-3581201
Biological Activity
AZ12799734 (AZ-12799734) is a pan BMP/TGFβ inhibitor that potently inhibits ligand activated SMAD3/4 transcription with IC50 of 47 nM.
Physicochemical Properties
M.Wt
370.427
Formula
C18H18N4O3S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-((4-((2,6-dimethylpyridin-3-yl)oxy)pyridin-2-yl)amino)benzenesulfonamide
References
1. Spender LC, et al. Mol Pharmacol.
2. Goldberg FW, et al. J Med Chem.
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