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Chemical Structure : AgrA inhibitor F19
Catalog No.: PC-35816Not For Human Use, Lab Use Only.
AgrA inhibitor F19 is a small-molecule AgrA inhibitor that act as antivirulence agent against Gram-positive pathogens, blocks staphylococcal transcription factor AgrA from binding to its promoter and inhibits toxin and virulence factor transcription.
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AgrA inhibitor F19 is a small-molecule AgrA inhibitor that act as antivirulence agent against Gram-positive pathogens, blocks staphylococcal transcription factor AgrA from binding to its promoter and inhibits toxin and virulence factor transcription.
AgrA inhibitor F19 binds to C-terminal DNA-binding domain (AgrA_C) from Staphylococcus epidermidis with an affinity of 2.7 uM.
AgrA inhibitor F19 potentiates β-lactam antibiotics in a MRSA wound model.
| M.Wt | 370.489 | |
| Formula | C23H30O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Greenberg M, et al. Sci Rep. 2018 Oct 1;8(1):14578.
2. Khodaverdian V, et al. Antimicrob Agents Chemother. 2013 Aug;57(8):3645-52.
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