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Albiglutide TFA

Chemical Structure : Albiglutide TFA

CAS No.:

Albiglutide TFA (GSK-716155 trifluoroacetate)

Catalog No.: PC-27455Not For Human Use, Lab Use Only.

Albiglutide TFA (GSK-716155) is a GLP-1 analog and long-acting, dipeptidyl peptidase-4-resistant GLP-1 receptor agonist, stimulates cAMP production through the GLP-1 receptor and induces insulin secretion from INS-1 cells in vitro and in animal models.

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Biological Activity

Albiglutide TFA (GSK-716155) is a GLP-1 analog and long-acting, dipeptidyl peptidase-4-resistant GLP-1 receptor agonist, stimulates cAMP production through the GLP-1 receptor and induces insulin secretion from INS-1 cells in vitro and in animal models.

Physicochemical Properties

M.Wt 3284.6
Formula C148H223N39O46
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-OH

References

1. Rosenstock J, et al. Diabetes Care. 2009 Oct;32(10):1880-6.

2. Matthews JE, et al. J Clin Endocrinol Metab. 2008 Dec;93(12):4810-7.

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