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Chemical Structure : Alda-1
CAS No.: 349438-38-6
Catalog No.: PC-45563Not For Human Use, Lab Use Only.
Alda-1 is a small-molecule activator of ALDH2, particularly effective activator of ALDH2*2 (EC50= 20 uM, increases the activity of the mutant, ALDH2*2 (11-fold).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | $298 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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Alda-1 is a small-molecule activator of ALDH2, particularly effective activator of ALDH2*2 (EC50= 20 uM, increases the activity of the mutant, ALDH2*2 (11-fold).
Alda-1 causes slight inhibition of GTN denitration and did not increase GTN-induced sGC activation in the presence of either variant; no effect on ADH1.
| M.Wt | 324.1588 | |
| Formula | C15H11Cl2NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 51 mg/mL |
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| Chemical Name/SMILES |
Benzamide, N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichloro- |
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1. Chen CH, et al. Science. 2008 Sep 12;321(5895):1493-5.
2. Beretta M, et al. J Biol Chem. 2010 Jan 8;285(2):943-52.
3. Ning S, et al. Radiat Res. 2012 Jul;178(1):69-74.
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