Catalog No.: PC-28026Not For Human Use, Lab Use Only.
Ampyrone (4-Aminoantipyrine) is a nonsteroidal antiinflammatory drug, PGE2-dependent blocker and inhibitor of cyclooxygenase (COX), also is a direct agonist of human Tyrosinase (TYR), increases catalytic activity of both hTYRWT and hTYRP406L with EC50 of 0.67 and 3.57 mM, respectively.
Ampyrone (4-Aminoantipyrine) is a nonsteroidal antiinflammatory drug, PGE2-dependent blocker and inhibitor of cyclooxygenase (COX), also is a direct agonist of human Tyrosinase (TYR), increases catalytic activity of both hTYRWT and hTYRP406L with EC50 of 0.67 and 3.57 mM, respectively.
Physicochemical Properties
M.Wt
203.25
Formula
C11H13N3O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-Amino-2,3-dimethyl-1-phenyl-3-pyrazol-5-one
References
1. Berno CR, et al. Mutat Res Genet Toxicol Environ Mutagen. 2016 Jul;805:19-24.
2. Dolinska MB, et al. JCI Insight. 2026 Jun 18;11(16):e202947.
