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Chemical Structure : Arimoclomol
CAS No.: 289893-25-0
Catalog No.: PC-60544Not For Human Use, Lab Use Only.
Arimoclomol (BRX-220) is a nontoxic heat shock protein (HSP) coinducer and potentiator of the heat shock response.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $248 | In stock | |
| 50 mg | $398 | In stock | |
| 100 mg | Get quote |
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Arimoclomol (BRX-220) is a nontoxic heat shock protein (HSP) coinducer and potentiator of the heat shock response.
Arimoclomol (BRX-220) significantly increases pancreatic levels of HSP60 and HSP72 in vivo, significantly delays disease progression and prevents protein aggregation in the SOD1 mouse model of ALS.
| M.Wt | 313.782 | |
| Formula | C14H20ClN3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(R,Z)-3-(chloro((2-hydroxy-3-(piperidin-1-yl)propoxy)imino)methyl)pyridine 1-oxide |
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1. Kieran D, et al. Nat Med. 2004 Apr;10(4):402-5.
2. Parfitt DA, et al. Cell Death Dis. 2014 May 22;5:e1236.
3. Rakonczay Z Jr, et al. Free Radic Biol Med. 2002 Jun 15;32(12):1283-92.
4. Kalmar B, et al. J Neurochem. 2008 Oct;107(2):339-50.
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