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Chemical Structure : Artefenomel
Catalog No.: PC-62987Not For Human Use, Lab Use Only.
Artefenomel (OZ439) is a novel, next-generation antimalarial ozonide that demonstrates high potentcy against P. falciparum in vitro and P. berghei in vivo (K1/NF54, IC50=2.0/3.2 nM)..
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Artefenomel (OZ439) is a novel, next-generation antimalarial ozonide that demonstrates high potentcy against P. falciparum in vitro and P. berghei in vivo (K1/NF54, IC50=2.0/3.2 nM).
Parasite Infection
Phase 2 Clinical
| M.Wt | 469.622 | |
| Formula | C28H39NO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Dong Y, et al. J Med Chem. 2017 Apr 13;60(7):2654-2668.
2. Kim HS, et al. J Med Chem. 2017 Apr 13;60(7):2651-2653.
3. Macintyre F, et al. BMC Med. 2017 Oct 9;15(1):181.
4. Yang T, et al. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4501-10.
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