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Atg4B inhibitor 21f

Chemical Structure : Atg4B inhibitor 21f

CAS No.: 2765008-88-4

Atg4B inhibitor 21f

Catalog No.: PC-72137Not For Human Use, Lab Use Only.

Atg4B inhibitor 21f is a potent competitive inhibitor for Atg4B with Ki of 3.1 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Atg4B inhibitor 21f is a potent competitive inhibitor for Atg4B with Ki of 3.1 uM.
Atg4B inhibitor 21f enhanced the anticancer activity of anti-CRPC drugs via autophagy inhibition.

Physicochemical Properties

M.Wt 330.468
Formula C21H30O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-4-oxo-4-(4-undecylphenyl)but-2-enoic acid

References

1. Yudai Kudo, et al. J Med Chem. 2022 Mar 4. doi: 10.1021/acs.jmedchem.1c02113.

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