Chemical Structure : Aurachin D
CAS No.:
108354-13-8
Aurachin D
Catalog No.: PC-28617Not For Human Use, Lab Use Only.
Aurachin D is a smal molecule Mycobacterium tuberculosis (Mtb) cytochrome bd oxidase (Cyt-bd) inhibitor, exhibits inhibitory effects against Gram-positive bacteria and fungi with IC50 value of 0.1 μM against Escherichia coli and IC50 ranging from 0.13 to 33 μM against Mycobacterium tuberculosis, blocks the electron transfer process, disrupts the respiratory chain and energy metabolism of pathogens.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
Aurachin D is a smal molecule Mycobacterium tuberculosis (Mtb) cytochrome bd oxidase (Cyt-bd) inhibitor, exhibits inhibitory effects against Gram-positive bacteria and fungi with IC50 value of 0.1 μM against Escherichia coli and IC50 ranging from 0.13 to 33 μM against Mycobacterium tuberculosis, blocks the electron transfer process, disrupts the respiratory chain and energy metabolism of pathogens.
Physicochemical Properties
|
M.Wt
|
363.55
|
|
Formula
|
C25H33NO
|
|
Appearance
|
Solid
|
|
CAS No.
|
|
|
Storage
|
- Solide Powder
-
-20°C 12 Months; 4°C 6 Months
|
- In Solvent
-
-80°C 6 Months; -20°C 6 Months
|
|
Shipping
|
|
|
Solubility
|
10 mM in DMSO
|
|
Chemical Name/SMILES
|
2-Methyl-3-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)quinolin-4(1H)-one
|
References
1. Lawer A, et al. ACS Med Chem Lett. 2022 Sep 26;13(10):1663-1669.
Contact Us
sales@probechem.com
