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Chemical Structure : Axitinib
CAS No.: 319460-85-0
Catalog No.: PC-21859Not For Human Use, Lab Use Only.
Axitinib (AG-013736) is a potent, multi-targeted tyrosine kinase inhibitor with IC50 of 0.1, 0.2, 0.1-0.3, 1.6 nM for VEGFR1, VEGFR2, VEGFR3 and PDGFRβ, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $88 | In stock | |
| 200 mg | $128 | In stock | |
| 500 mg | $188 | In stock | |
| 1 g | Get quote |
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Axitinib (AG-013736) is a potent, multi-targeted tyrosine kinase inhibitor with IC50 of 0.1, 0.2, 0.1-0.3, 1.6 nM for VEGFR1, VEGFR2, VEGFR3 and PDGFRβ, respectively.
| M.Wt | 386.47 | |
| Formula | C22H18N4OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide |
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1. Fenton BM, et al. Cancer Res. 2007 Oct 15;67(20):9921-8.
2. Hu-Lowe DD, et al. Clin Cancer Res. 2008 Nov 15;14(22):7272-83.
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