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Chemical Structure : BAL-0028
Catalog No.: PC-22057Not For Human Use, Lab Use Only.
BAL-0028 (BAL0028) is a potent, selective and reversible inhibitor of NLRP3 activation with IC50 of 25 nM, binds to the NACHT domain of NLRP3 with Kd of 104-123 nM.
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BAL-0028 (BAL0028) is a potent, selective and reversible inhibitor of NLRP3 activation with IC50 of 25 nM, binds to the NACHT domain of NLRP3 with Kd of 104-123 nM.
BAL-0028 is distinct from MCC950 and includes specific site interactions.
| M.Wt | 403.46 | |
| Formula | C24H22FN3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. George Hartman, et al. Bioorg Med Chem Lett. 2024 Apr 1:102:129675.
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