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BAL30072

Chemical Structure : BAL30072

CAS No.: 941285-15-0

BAL30072 (BAL 30072)

Catalog No.: PC-62571Not For Human Use, Lab Use Only.

BAL30072 is a monocyclic beta-lactam antibiotic that shows potent activity against MDR Pseudomonas aeruginosa and Acinetobacter sp. Isolates with MIC90 of 8 and 4 ug/ml.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BAL30072 is a monocyclic beta-lactam antibiotic that shows potent activity against MDR Pseudomonas aeruginosa and Acinetobacter sp. Isolates with MIC90 of 8 and 4 ug/ml.
    BAL30072 is also active against many species of MDR isolates of the Enterobacteriaceae family, including isolates that had a class A carbapenemase or a metallo-beta-lactamase.
    BAL30072 trigger the spheroplasting and lysis of Escherichia coli rather than the formation of extensive filaments.

    Physicochemical Properties

    M.Wt 518.472
    Formula C16H18N6O10S2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (aZ)-2-Amino-a-[[(1,4-dihydro-1,5-dihydroxy-4-oxo-2-pyridinyl)methoxy]imino]-N-[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]-4-thiazoleacetamide

    References

    1. Page MG, et al. Antimicrob Agents Chemother. 2010 Jun;54(6):2291-302.

    2. Russo TA, et al. J Antimicrob Chemother. 2011 Apr;66(4):867-73.

    3. Mima T, et al. Int J Antimicrob Agents. 2011 Aug;38(2):157-9.

    4. Hornsey M, et al. Int J Antimicrob Agents. 2013 Oct;42(4):343-6.

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