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Chemical Structure : BAY-298
Catalog No.: PC-72913Not For Human Use, Lab Use Only.
BAY-298 (BAY298) is a highly potent, selective luteinizing hormone receptor (LH-R) inhibitor with IC50 of 96 nM and 23 nM for hLH-R and rLH-R, respectively.
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BAY-298 (BAY298) is a highly potent, selective luteinizing hormone receptor (LH-R) inhibitor with IC50 of 96 nM and 23 nM for hLH-R and rLH-R, respectively.
BAY-899 suppressed hLH-induced ovarian marker gene expression in cetrorelix-treated female rats.
BAY-899 counteracted the hLH-induced increase in plasma testosterone levels in male rats, and reduced serum estradiol levels in female rats
| M.Wt | 473.932 | |
| Formula | C27H21ClFN3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lars Wortmann, et al. J Med Chem. 2019 Nov 27;62(22):10321-10341.
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