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BC8-15C

Chemical Structure : BC8-15C

CAS No.: 901263-25-0

BC8-15C (BC 8-15C)

Catalog No.: PC-23481Not For Human Use, Lab Use Only.

BC8-15C is a potent, selective PDE11A inhibitor with IC50 of 0.08 uM in in vitro enzyme assays, also inhibits PDE4A with IC50 of 0.13 uM, shows little to no activity against PDE1, PDE2, PDE3, PDE5, PDE9, PDE10.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BC8-15C is a potent, selective PDE11A inhibitor with IC50 of 0.08 uM in in vitro enzyme assays, also inhibits PDE4A with IC50 of 0.13 uM, shows little to no activity against PDE1, PDE2, PDE3, PDE5, PDE9, PDE10.

    Physicochemical Properties

    M.Wt 303.37
    Formula C18H17N5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    3-ethyl-N-(m-tolyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-amine

    References

    1. Demirbas D, et al. PLoS One. 2013 Aug 14;8(8):e71279.

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