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Chemical Structure : BCL6 inhibitor 8c
Catalog No.: PC-61016Not For Human Use, Lab Use Only.
A novel potent, in vivo-active BCL6 inhibitor with IC50 of 0.1 uM in ELISA assays.
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A novel potent, in vivo-active BCL6 inhibitor with IC50 of 0.1 uM in ELISA assays; exhibits good cellular BCL6BTB/ BCoR PPI inhibitory activity in the submicromolar range (M2H IC50=0.72 uM), showed a good pharmacokinetic profile, which is acceptable for both in vitro and in vivo studies.
| M.Wt | 417.846 | |
| Formula | C20H20ClN3O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yasui T, et al. Bioorg Med Chem. 2017 Sep 1;25(17):4876-4886.
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