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Chemical Structure : BCTC
CAS No.: 393514-24-4
Catalog No.: PC-45764Not For Human Use, Lab Use Only.
BCTC is a highly potent, selective, CNS-penetrant TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 with IC50 values of 35 and 6 nM, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg (Free Sample) | $18 | In stock | |
| 10 mg | $78 | In stock | |
| 25 mg | $128 | In stock | |
| 50 mg | $218 | In stock | |
| 100 mg | Get quote |
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BCTC is a highly potent, selective, CNS-penetrant TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 with IC50 values of 35 and 6 nM, respectively.
BCTC shows selectivity against 63 other receptor, enzyme, transporter, and ion channel targets; orally bioavailable.
| M.Wt | 372.8917 | |
| Formula | C20H25ClN4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1-Piperazinecarboxamide, 4-(3-chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]- |
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1. Valenzano KJ, et al. J Pharmacol Exp Ther. 2003 Jul;306(1):377-86.
2. Gavva NR, et al. Mol Pharmacol. 2005 Dec;68(6):1524-33.
3. Yamamoto M, et al. World J Gastroenterol. 2016 Nov 28;22(44):9752-9764.
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