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Chemical Structure : BD-1063 dhydrochloride
CAS No.: 206996-13-6
Catalog No.: PC-45420Not For Human Use, Lab Use Only.
BD-1063 dhydrochloride (BD1063) is a potent, selective sigma-1 receptor antagonist with binding Ki of 9 nM.
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|---|---|---|---|
| 10 mg | $108 | In stock | |
| 25 mg | $188 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | Get quote |
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BD-1063 dhydrochloride (BD1063) is a potent, selective sigma-1 receptor antagonist with binding Ki of 9 nM.
BD-1063 displays >49-fold selectivity over the sigma-2 receptor.
BD-1063 significantly reverses the neuroprotective effect of DHEA-S against NMDA-induced neurotoxicity in rat hippocampal neurons.
| M.Wt | 346.1233 | |
| Formula | C13H20Cl4N2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
100 mM in H2O |
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| Chemical Name/SMILES |
Piperazine, 1-[2-(3,4-dichlorophenyl)ethyl]-4-methyl-, hydrochloride (1:2) |
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1. Matsumoto RR, et al. Eur J Pharmacol. 2001 May 11;419(2-3):163-74.
2. Matsumoto RR, et al. Eur J Pharmacol. 1995 Jul 14;280(3):301-10.
3. Wu Z, et al. J Biol Chem. 2008 Oct 17;283(42):28198-215.
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