Chemical Structure : BI-2545
CAS No.:
2162961-71-7
BI-2545
(BI2545;BI 2545)
Catalog No. : PC-60142Not For Human Use, Lab Use Only.
BI-2545 is a novel potent, selective, orally available Autotaxin inhibitor with IC50 of 2.1 and 3.4 nM for huamn and rat ATX, respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6014201
Biological Activity
BI-2545 is a novel potent, selective, orally available Autotaxin inhibitor with IC50 of 2.1 and 3.4 nM for huamn and rat ATX, respectively.
Physicochemical Properties
M.Wt
527.427
Formula
C23H19F6N5O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
3,5-bis(trifluoromethyl)benzyl (1R,5S,6r)-6-((1H-benzo[d][1,2,3]triazole-5-carboxamido)methyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate
References
1. Christian A. Kuttruff, et al. ACS Med. Chem. Lett.
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