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BI-4916

Chemical Structure : BI-4916

CAS No.: 2244451-48-5

BI-4916 (BI 4916, BI4916)

Catalog No.: PC-72879Not For Human Use, Lab Use Only.

BI-4916 (BI-4916) is the prodrug of BI-4924, which is a potent, selective NADH/NAD+-competitive PHGDH inhibitor with IC50 of 2 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BI-4916 (BI-4916) is the prodrug of BI-4924, which is a potent, selective NADH/NAD+-competitive PHGDH inhibitor with IC50 of 2 nM.

Physicochemical Properties

M.Wt 527.413
Formula C23H24Cl2N2O6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Ethyl 2-{4-[(1S)-1-[(4,5-dichloro-1,6-dimethyl-1H-indol-2-yl)formamido]-2-hydroxyethyl]benzenesulfonyl}acetate

References

1. Harald Weinstabl, et al. J Med Chem. 2019 Sep 12;62(17):7976-7997.

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