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Chemical Structure : BI 6901
CAS No.: 2040401-92-9
Catalog No.: PC-35030Not For Human Use, Lab Use Only.
BI 6901 is a potent, selective CCR10 antagonist with Aequorin Ca2+ flux pIC50 of 9.0, shows high selectivity over other GPCRs.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $358 | In stock | |
| 10 mg | $558 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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BI 6901 is a potent, selective CCR10 antagonist with Aequorin Ca2+ flux pIC50 of 9.0, shows high selectivity over other GPCRs.
BI 6901 inhibits the CCL27 dependent chemotaxis of Ba/F3 cells stably transfected with human CCR10 with pIC50 of 9.0.
BI 6901 is efficacious in a murine model of DNFB contact hypersensitivity, inhibits DNFB stimulated inflammatory response in sensitized Balb-C mice.
| M.Wt | 453.561 | |
| Formula | C23H27N5O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-[(2R)-4-(2-cyanopyrrol-1-yl)-1-(4-methylpiperidin-1-yl)-1-oxobutan-2-yl]-1H-indole-4-sulfonamide |
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1. Abeywardane A, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5277-5283.
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