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Chemical Structure : BIO-7662
Catalog No.: PC-70014Not For Human Use, Lab Use Only.
BIO-7662 (BIO7662) is a potent, highly selective α4β1 integrin antagonist with Kd of <10 pM.
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BIO-7662 (BIO7662) is a potent, highly selective α4β1 integrin antagonist with Kd of <10 pM.
The rate of BIO7662 binding is dependent on the metal ion concentration; directly competes with VCAM-1, CS-1, and BIO1211 for binding to the integrin.
| M.Wt | 748.896 | |
| Formula | C38H48N6O8S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Chen LL, et al. J Biol Chem. 2001 Sep 28;276(39):36520-9.
2. Egger LA, et al. J Pharmacol Exp Ther. 2003 Sep;306(3):903-13.
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