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Chemical Structure : BLU-554
CAS No.: 1707289-21-1
Catalog No.: PC-42173Not For Human Use, Lab Use Only.
BLU-554 (Fisogatinib, BLU554) is a novel potent, highly selective and orally bioavailable inhibitor of FGFR4 with IC50 of 5 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg (Free Sample) | $28 | In stock | |
| 10 mg | $98 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $248 | In stock | |
| 100 mg | Get quote |
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BLU-554 (Fisogatinib, BLU554) is a novel potent, highly selective and orally bioavailable inhibitor of FGFR4 with IC50 of 5 nM.
BLU-554 inhibits hepatocellular carcinoma (HCC) with FGFR4 pathway activation.
BLU-554 targets FGFR4 while sparing other members of the FGFR family and showing little to no inhibition of all other kinases.
| M.Wt | 503.3777 | |
| Formula | C24H24Cl2N4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 25 mg/mL |
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| Chemical Name/SMILES |
2-Propenamide, N-[(3S,4S)-3-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-quinazolinyl]amino]tetrahydro-2H-pyran-4-yl]- |
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1. Richard Kim, et al. EJC. December 2016, Volume 69, Supplement 1, Page S41.
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