Chemical Structure : BMS-1001 hydrochloride
CAS No.:
2113650-04-5
BMS-1001 hydrochloride
(BMS 1001 HCl, BMS1001 HCl)
Catalog No.: PC-70035Not For Human Use, Lab Use Only.
BMS-1001 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 2.25 nM in a homogenous time-resolved fluorescence binding assay.
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| 5 mg | $138 | In stock | |
| 10 mg | $218 | In stock | |
| 25 mg | $378 | In stock | |
| 50 mg | $588 | In stock | |
| 100 mg | | Get quote | |
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Purity & Documentation Purity:
>98% (HPLC)
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Biological Activity
BMS-1001 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 2.25 nM in a homogenous time-resolved fluorescence binding assay.
Physicochemical Properties
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M.Wt
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667.099
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Formula
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C35H35ClN2O7HCl
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20 °C 12 Months; 4°C 6 Months
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- In Solvent
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-80 °C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO (6.67 mg/mL)
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Chemical Name/SMILES
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(2-((3-cyanobenzyl)oxy)-4-((3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methylbenzyl)oxy)-5-methylbenzyl)-D-serine hydrochloride
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References
1. Guzik K, et al. J Med Chem. 2017 Jul 13;60(13):5857-5867.
2. Chupak, L.S., and Zheng, X. Compounds useful as immunomodulators. PCT/US2014/053695, (2015).
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