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BMS-698861

Chemical Structure : BMS-698861

CAS No.:

BMS-698861 (BMS698861)

Catalog No.: PC-62912Not For Human Use, Lab Use Only.

BMS-698861 is a potent γ-secretase modulator (GSM) that decreases levels of all the peptides, Aβ1-40, Aβ1-42, Aβ1-38, Aβ1-37 and Aβ1-x, results in APP-CTFβ and APP-CTFα accumulation in brain.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    BMS-698861 is a potent γ-secretase modulator (GSM) that decreases levels of all the peptides, Aβ1-40, Aβ1-42, Aβ1-38, Aβ1-37 and Aβ1-x, results in APP-CTFβ and APP-CTFα accumulation in brain.

    Physicochemical Properties

    M.Wt 478.923
    Formula C21H20ClFN4O4S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R)-2-((4-chloro-N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)phenyl)sulfonamido)-3-cyclopropylpropanamide

    References

    1. Toyn JH, et al. Int J Alzheimers Dis. 2014;2014:431858.

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