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Chemical Structure : BMS-813160
CAS No.: 1286279-29-5
Catalog No.: PC-72668Not For Human Use, Lab Use Only.
BMS-813160 (BMS 813160) a potent and selective CCR2/5 dual antagonist with binding IC50 of 6.2/3.6 nM, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $198 | In stock | |
| 25 mg | $328 | In stock | |
| 100 mg | $798 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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BMS-813160 (BMS 813160) a potent and selective CCR2/5 dual antagonist with binding IC50 of 6.2/3.6 nM, respectively.
BMS-813160 had excellent oral bioavailability and exhibited low clearance in dog and cyno.
BMS-813160 inhibited the migration of inflammatory monocytes and macrophages in the mouse thioglycollate-induced peritonitis model.
| M.Wt | 484.649 | |
| Formula | C25H40N8O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-((1R,2S,5R)-2-((S)-3-((7-(tert-butyl)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)-2-oxopyrrolidin-1-yl)-5-(tert-butylamino)cyclohexyl)acetamide |
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1. Cherney RJ, et al. ACS Med Chem Lett. 2021 Oct 15;12(11):1753-1758.
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