Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : BMS-871
Catalog No.: PC-63562Not For Human Use, Lab Use Only.
BMS-871 (BMS871) is a potent, orally active pan-Notch inhibitor with IC50 of 4/1/4/3 nM for Notch1/2/3/4, respectively.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
BMS-871 (BMS871) is a potent, orally active pan-Notch inhibitor with IC50 of 4/1/4/3 nM for Notch1/2/3/4, respectively.
BMS-871 inhibits TALL-1 tumor cell proliferation with IC50 of 4 nM.
BMS-871displays robust in vivo efficacy in Notch-dependent leukemia and triple negative breast cancer xenografts.
| M.Wt | 536.555 | |
| Formula | C29H27F3N4O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Shan W, et al. Bioorg Med Chem Lett. 2015 May 1;25(9):1905-9.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
