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BMS-884775

Chemical Structure : BMS-884775

CAS No.: 1557206-59-3

BMS-884775 (BMS884775)

Catalog No.: PC-63561Not For Human Use, Lab Use Only.

BMS-884775 is a potent, selective P2Y1 antagonist with IC50 of 0.12 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BMS-884775 is a potent, selective P2Y1 antagonist with IC50 of 0.12 nM; demonstrates similar antithrombotic efficacy with less bleeding compared with known P2Y12 antagonist prasugrel.

Physicochemical Properties

M.Wt 689.223
Formula C36H35ClF2N6O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(5-Chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl)-1-(2-{1'-(2,2-dimethylpropyl)-5-fluoro-4-(4-fluorophenyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4'-piperidine]-1-yl}phenyl)urea

References

1. Yang W, et al. J Med Chem. 2014 Jul 24;57(14):6150-64.

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