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BMS136

Chemical Structure : BMS136

CAS No.: 1675203-24-3

BMS136

Catalog No.: PC-49098Not For Human Use, Lab Use Only.

BMS136 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 96.7 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BMS136 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 96.7 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.

Physicochemical Properties

M.Wt 418.493
Formula C25H26N2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-((4-(((2-hydroxyethyl)amino)methyl)-3,5-dimethoxyphenoxy)methyl)-[1,1'-biphenyl]-2-carbonitrile

References

1. Marawan Ahmed, et al. BMC Chem. 2022 Jun 27;16(1):49.

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