BMS136 | PD-L1 inhibitor | Probechem Biochemicals

Chemical Structure : BMS136

BMS136 (BMS-136)

Catalog No.: PC-49098Not For Human Use, Lab Use Only.

BMS136 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 96.7 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.

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Biological Activity

BMS136 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 96.7 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.

Physicochemical Properties

M.Wt	418.493
Formula	C25H26N2O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((4-(((2-hydroxyethyl)amino)methyl)-3,5-dimethoxyphenoxy)methyl)-[1,1'-biphenyl]-2-carbonitrile

References

1. Marawan Ahmed, et al. BMC Chem. 2022 Jun 27;16(1):49.

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BMS136 (BMS-136)

Biological Activity

Physicochemical Properties

References

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