Catalog No.: PC-63269Not For Human Use, Lab Use Only.
BMS433771 (BMS-433771) is a potent, orally active RSV fusion inhibitor, exhibits excellent potency against multiple laboratory and clinical isolates of both group A and B viruses with mean EC50 of 20 nM.
BMS433771 (BMS-433771) is a potent, orally active RSV fusion inhibitor, exhibits excellent potency against multiple laboratory and clinical isolates of both group A and B viruses with mean EC50 of 20 nM.
BMS433771 inhibits the fusion of lipid membranes during both the early virus entry stage and late-stage syncytium formation.
A series of single amino acid mutations in the F1 subunit of the fusion protein confers resistance to BMS433771.
