BMX inhibitor 11i | BMX inhibitor | Probechem Biochemicals

Chemical Structure : BMX inhibitor 11i

BMX inhibitor 11i (BMX-IN-2)

Catalog No.: PC-27275Not For Human Use, Lab Use Only.

BMX inhibitor 11i (BMX-IN-2) is a potent, selective TEC family member BMX kinase with IC50 of 1.78 nM and EC50 of 98 nM in NanoBRET assays, 20-fold selective over BTK.

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Biological Activity

BMX inhibitor 11i (BMX-IN-2) is a potent, selective TEC family member BMX kinase with IC50 of 1.78 nM and EC50 of 98 nM in NanoBRET assays, 20-fold selective over BTK.

Physicochemical Properties

M.Wt	422.89
Formula	C21H15ClN4O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-(3-Acrylamidophenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-5-chlorothiophene-2-carboxamide

References

1. Liang XJ, et al. J Med Chem. 2026 Jul 13. doi: 10.1021/acs.jmedchem.6c01366.

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BMX inhibitor 11i (BMX-IN-2)

Biological Activity

Physicochemical Properties

References

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