BMX inhibitor B6a | BMX inhibitor | Probechem Biochemicals

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Chemical Structure : BMX inhibitor B6a

BMX inhibitor B6a (BMX-IN-3)

Catalog No.: PC-27276Not For Human Use, Lab Use Only.

BMX inhibitor B6a (BMX-IN-3) is a potent, selective and irreversible BMX kinase with IC50 of 12 nM, displays good antiproliferative activities in various cancer cell lines, promotes cell cycle arrest and apoptosis, triggers protective autophagy, and suppresses the BMX/AKT/mTOR pathway.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	467.55
Formula	C22H25N7O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N2-(3-phenoxyphenyl)-N4-(1-(vinylsulfonyl)piperidin-3-yl)-1,3,5-triazine-2,4,6-triamine

References

1. Nan Wang, et al. J Med Chem. 2025 Feb 27;68(4):4196-4216.

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BMX inhibitor B6a (BMX-IN-3)

Biological Activity

Physicochemical Properties

References

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