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Chemical Structure : BPR1M97
CAS No.: 2059904-66-2
Catalog No.: PC-38589Not For Human Use, Lab Use Only.
BPR1M97 is a dual-acting mu-opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist with Ki values of 1.8 and 4.2 nM, respectively.
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| 50 mg | $728 | In stock | |
| 100 mg | $1250 | In stock | |
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BPR1M97 is a dual-acting mu-opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist with Ki values of 1.8 and 4.2 nM, respectively.
BPR1M97 elicited full agonist properties for all cell-based assays tested in MOP-expressing cells.
BPR1M97 acted as a G protein-biased agonist for NOP.
BPR1M97 initiated faster antinociceptive effects after subcutaneous injection and elicited better analgesia in cancer-induced pain than morphine.
BPR1M97 caused less respiratory, cardiovascular, and gastrointestinal dysfunction, compared with morphine.
| M.Wt | 349.25 | |
| Formula | C18H18Cl2N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3,4-Dichloro-N-[(1,2,3,4-tetrahydro-2-methyl-1-isoquinolinyl)methyl]benzamide |
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1. Po-Kuan Chao, et al. Neuropharmacology. 2020 Apr;166:107678.
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