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Chemical Structure : BR102910
CAS No.: 2505339-54-6
Catalog No.: PC-72074Not For Human Use, Lab Use Only.
BR102910 (BR 102910) is a novel potent, selective, oral fibroblast activation protein (FAP) inhibitor with IC50 of 1 nM.
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BR102910 (BR 102910) is a novel potent, selective, oral fibroblast activation protein (FAP) inhibitor with IC50 of 1 nM.
BR102910 displays high selectivity over DPPIV and prolyl oligopeptidase (PREP).
BR102910 demonstrated exceptional profiles and satisfactory FAP inhibition efficacy in vivo FAP inhibition study using C57BL/6J mice.
| M.Wt | 459.293 | |
| Formula | C18H14Cl2F2N4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-N-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)-2-(3,4-dichlorobenzyl)thiazole-4-carboxamide |
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1. Hui Jin Jung, et al. Bioorg Med Chem Lett. 2021 Apr 1;37:127846.
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