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Chemical Structure : BR103
Catalog No.: PC-61771Not For Human Use, Lab Use Only.
BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 ± 8 nM.
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BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 nM.
BR103 displays high selectivity for C3aR over C5aR.
BR103 induces paw oedema and mast cell activation in vivo in rats.
| M.Wt | 448.527 | |
| Formula | C24H28N6O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lohman RJ, et al. Nat Commun. 2017 Aug 24;8(1):351.
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