BRAF inhibitor 13 |CAS:1093100-40-3 Probechem Biochemicals

Chemical Structure : BRAF inhibitor 13

CAS No.: 1093100-40-3

BRAF inhibitor 13 (BRAF-IN-13)

Catalog No.: PC-70025Not For Human Use, Lab Use Only.

A potent and selective B-Raf inhibitor with IC50 of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.

Packing	Price	Stock
5 mg	$88	In stock
10 mg	$128	In stock
25 mg	$218	In stock
50 mg	$358	In stock
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Biological Activity

BRAF inhibitor 13 (BRAF-IN-13) is a potent and selective B-Raf inhibitor with IC50 of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.
BRAF inhibitor 13 (BRAF-IN-13) induces proliferation and hyperplasia in normal tissues of mice.

Physicochemical Properties

M.Wt	478.944
Formula	C26H19ClN8
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N5-(3-(9H-purin-6-yl)pyridin-2-yl)-N1-(4-chlorophenyl)-6-methylisoquinoline-1,5-diamine

References

1. Wang X, et al. J Med Chem. 2012 Sep 13;55(17):7332-41.

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BRAF inhibitor 13 (BRAF-IN-13)

Biological Activity

Physicochemical Properties

References

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