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BRD1172

Chemical Structure : BRD1172

CAS No.: 1597438-86-2

BRD1172 (BRD 1172)

Catalog No.: PC-62878Not For Human Use, Lab Use Only.

BRD1172 is a highly selective, potent, reversible, ATP-competitive GSK3 inhibitor with IC50 of 3 nM/10 nM for GSK3α/GSK3β, respectively..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

BRD1172 is a highly selective, potent, reversible, ATP-competitive GSK3 inhibitor with IC50 of 3 nM/10 nM for GSK3α/GSK3β, respectively.

Physicochemical Properties

M.Wt 391.394
Formula C20H20F3N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4R)-4-(2-methoxyphenyl)-7,7-dimethyl-3-(trifluoromethyl)-2,4,6,8-tetrahydro-1H-pyrazolo[3,4-b]quinolin-5-one

References

1. Wagner FF, et al. ACS Chem Biol. 2016 Jul 15;11(7):1952-63.

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